Advancing Equine Care with Pegasus Orthobiologics

Pegasus is taking inconsistency and uncertainty out of orthobiologics and replacing it with transparency and precision

Why Orthobiologics?

Historically, corticosteroid injections have been used to manage equine lameness. While steroids may temporarily relieve pain and improve clinical symptoms, they can obscure ongoing musculoskeletal issues and give the false impression of recovery. This pain-masking effect can lead to overuse of the affected joints, potentially worsening injuries and accelerating degenerative conditions. Moreover, steroid use is especially dangerous in horses with metabolic dysregulation (such as EMS or PPID), where it can trigger laminitis, and in those with neurological conditions like EPM, where it may worsen disease through immune suppression.

Orthobiologics such as platelet-rich plasma (PRP) offer a safer alternative. Rather than merely mask pain, PRP aims to heal the joint by supporting the body's natural healing processes. This makes orthobiologics safer not only because they promote true healing, but also because they do not carry the same risks for horses with metabolic or neurological conditions. In this way, orthobiologics provide a more sustainable path to long-term soundness.
‍

Replacing Uncertainty With Clarity and Precision

Although PRP holds great promise, it has delivered inconsistent results. Because blood cell counts change throughout the day, and because every horse’s biology is different, the PRP produced stall-side with a commercial kit can vary widely. In fact, the same kit used on two horses, or even the same horse at different times, may yield very different results, and, in some cases, may not even produce PRP at all.

Pegasus changes this.

We use our state-of-the-art hematology analyzer to measure every component of the PRP. By knowing each patient’s exact cell counts, we can:

Standardize: Guarantee a therapeutic platelet dose with consistently low red and white cell levels.

Customize: Tailor the PRP to the unique biology of each horse and the tissue or joint being treated.

Advance Research: Generate patient data that drive essential research and advance the field of equine regenerative medicine.
‍
Our goal is to transform what has long been a hit-or-miss therapy into one that is consistent, precise, and reliable.

Services

Innovative Therapies Tailored for
Each Equine Athlete

Pegasus customizes biologics by precisely measuring each horse’s blood to ensure a therapeutic platelet dose, achieving a level of precision unmatched in sports medicine.

Pegasus PRP

PRP is an orthobiologic treatment that leverages the natural healing properties of your horse's blood to promote recovery and reduce inflammation. By concentrating platelets and growth factors such as TGF-β, PDGF, EGF, VEGF, and FGF, PRP initiates and accelerates the healing process. These growth factors attract stem cells, stimulate connective tissue growth, and promote the formation of new blood vessels, which deliver vital nutrients and oxygen to the injury site. While conventional PRP kits prepared stall-side vary in composition from patient to patient––and may even fail to produce platelet-rich plasma––Pegasus PRP is standardized. Every preparation is measured to ensure a defined platelet dose with minimal red and white blood cells. Pegasus PRP delivers a level of precision and consistency unmatched in equine sports medicine.

Cytokine Quantification

In addition to measuring cell counts in every PRP preparation, veterinarians can request cytokine quantification. Pegasus measures IL-1Ra, IL-10, TGF-β1, and TNF-α, providing deeper insight into each sample’s composition. This information offers quality control assurance, supports the development of customized treatments, and enables long-term monitoring of trends across patients. By collecting this data, Pegasus brings greater transparency to orthobiologics and contributes to ongoing research in equine regenerative medicine.

Collection and Delivery

Our technicians travel directly to the patient’s location, collect blood samples, and promptly transport them to our lab for meticulous processing in a sterile environment. The PRP syringes are then delivered when and where the veterinarian needs them enabling efficient, on-demand treatment with minimal disruption to busy schedules. By removing the need for additional staff, training, or specialized equipment, Pegasus makes it simple for veterinarians to provide standardized PRP without compromising time or budget.